Bills vs Chargers Odds, Picks, and Predictions Week 16: Low-Hanging Fruit

The Buffalo Bills are on the West Coast this weekend and get a stand-alone prime-time game tonight vs. the clean-house Los Angeles Chargers who will feature new head coach Giff Smith and rely on quarterback Easton Stick as a double-digit dog. 

With plenty of movement of both the side and total and coming off an embarrassing prime-time loss that got their coach canned, should bettors expect a different Chargers team than the one in Week 15?

I break down the NFL odds and offer my free NFL picks for Bills vs. Chargers on December 23.

Be sure to also check out our three favorite Bills vs Chargers prop picks and our Josh Allen spotlight!

Bills vs Chargers odds

Bills vs Chargers predictions

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